Pathogenesis: The salivary and sebaceous glands of certain animals, such as scorpions, produce toxic substances. Poisoning can occur through the consumption of contaminated quail (especially the head and skin), overuse of wolfberry-based remedies, or contact of wounds with venom. Scorpion venom contains various bioactive compounds, including diterpene alcohols like scorpion toxin and aglycone, which act similarly to digitalis. These compounds stimulate the vagus nerve, directly affect heart muscle tissue, and may lead to arrhythmia. Additionally, they have effects on the gastrointestinal tract, anticonvulsant properties, and local anesthetic actions. Catecholamines in the venom cause vasoconstriction and increased blood pressure, while sulfonium alkyl compounds can induce hallucinations and exhibit nicotinic-like effects on peripheral nerves.

Clinical Symptoms: The onset of symptoms typically occurs within 30 minutes to 1 hour after exposure. Common manifestations include gastrointestinal issues such as severe nausea, vomiting, abdominal pain, diarrhea, and even ascites, which may progress to shock. Cardiovascular and respiratory symptoms may include chest tightness, palpitations, cyanosis, and arrhythmias, with ECG changes such as ST segment elevation or T wave inversion, and conduction blocks. In severe cases, patients may develop A-Swiss syndrome, leading to respiratory and circulatory failure. Neurological symptoms may involve dizziness, headache, lethargy, excessive sweating, numbness in the lips and extremities, and convulsions. If venom enters the eye, it can cause irritation and potentially lead to blindness. Rarely, exfoliative dermatitis may also occur.

Diagnosis: A history of accidental ingestion or overdose of Chinese wolfberry herbs, along with characteristic poisoning symptoms, should raise suspicion of scorpion venom poisoning.

Treatment: Management follows general principles of poison removal and symptomatic care. Similar to digitalis toxicity, oral or intravenous potassium chloride may be administered. Atropine is used for conduction block. Fluid replacement and calming measures are essential. For patients experiencing respiratory or circulatory failure, appropriate supportive treatments should be provided. In cases of ocular contamination, eye drops or rinsing with comfrey juice can help alleviate symptoms.

Commonly known as "ha ha ha," there are numerous species of scorpions, with the most commonly found in China being the Chinese big clam and black clam. These creatures are often mistaken for harmless animals but can pose serious health risks if handled improperly.

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