First, it's essential to carefully regulate the amount of urea given to adult sheep. A daily dose of 10 to 15 grams is generally safe, as excessive amounts can be wasteful and even toxic. When calculating based on body weight, the recommended dosage is 0.02% to 0.05% of the sheep’s weight. For example, a 10 kg sheep should receive about 2 to 3 grams of urea per day. This ensures optimal utilization without overloading the animal’s system.

Second, when introducing urea for the first time, it's important to start gradually. Begin with just one-tenth of the total daily amount and slowly increase it over time. After about 10 days, once the rumen microorganisms have adapted, you can feed the full amount. This helps prevent digestive upset and ensures better absorption.

Third, never feed the entire daily dose of urea in one go. Instead, divide it into 2 to 3 smaller portions throughout the day. Dissolve the urea in water first, then spray it onto dry feed or mix it into concentrate feeds. This method helps ensure even distribution and reduces the risk of toxicity.

Fourth, avoid allowing sheep to drink water immediately after consuming feed containing urea. Wait at least 30 minutes before offering water. Never dissolve urea in drinking water, as this can lead to rapid absorption and potentially cause urea poisoning.

Fifth, urea works best when combined with sugar-rich feeds. It should be used alongside carbohydrate sources like molasses, corn flour, or dried melon powder. These feeds help support microbial activity in the rumen, enhancing the effectiveness of urea.

Sixth, while urea can supplement protein needs, it should not completely replace traditional protein sources. Continue feeding soybean meal, cottonseed cake, or other protein-rich feeds. However, note that soybean meal contains urease, which can speed up urea breakdown. Therefore, it should not be mixed directly with urea. Also, if the diet already contains more than 12% crude protein, additional urea may not be necessary.

Seventh, ensure the diet includes adequate levels of sulfur and phosphorus, as these minerals improve urea utilization. Phosphorus can be added through bone meal, while sulfur can come from potassium sulfate or sodium sulfate.

Eighth, avoid feeding urea to sick or underweight sheep. Similarly, do not give urea to animals that are extremely hungry, as this can increase the risk of toxicity.

Ninth, the use of urea must be consistent. Continuous feeding allows the rumen microorganisms to adapt and function optimally. If feeding is interrupted, reintroduce urea gradually to avoid shock to the system.

Tenth, in case of urea poisoning, immediate action is critical. Administer a rapid intravenous injection of 10% to 25% glucose solution, typically 100 to 200 ml. Additionally, giving 0.5 to 1 kg of vinegar via a stomach tube can provide effective first aid. Always seek veterinary assistance if symptoms persist.

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