First, it's important to carefully regulate the amount of urea given to adult sheep. A daily dose of 10 to 15 grams is typically sufficient. Giving too much can be wasteful and may lead to poisoning. When calculating based on body weight, the ideal daily dose is between 0.02% and 0.05% of the sheep’s weight. For example, a 10 kg sheep should receive about 2 to 3 grams of urea per day. This ensures safe and effective use without overloading the animal’s system.

Second, when introducing urea for the first time, it's best to start slowly. Begin with just one-tenth of the total daily amount and gradually increase the dosage over time. After about 10 days, once the rumen microorganisms have adapted, you can feed the full amount. This gradual approach helps prevent digestive upset and allows the microbial population to adjust properly.

Third, never feed all the urea at once. Instead, divide it into 2 or 3 smaller portions throughout the day. Dissolve the urea in water first before spraying it onto dry feed or mixing it into concentrate feed. This method ensures even distribution and better absorption by the animal.

Fourth, avoid letting sheep drink water immediately after consuming dry feed that contains urea. Wait at least 30 minutes before offering water. Never dissolve urea in drinking water, as this can cause serious poisoning. Urea must be ingested with food, not mixed directly into the water supply.

Fifth, always combine urea with a source of sugar or carbohydrates. This combination enhances the effectiveness of urea by supporting microbial activity in the rumen. You can mix it with high-carb feeds like molasses, corn flour, or dried melon powder. These ingredients help the microbes break down urea more efficiently and convert it into usable protein.

Sixth, while urea can supplement protein, it should not completely replace traditional protein sources. Continue feeding soybean meal, cottonseed cake, or other protein-rich feeds alongside urea. However, be cautious: bean-based feeds contain urease, an enzyme that breaks down urea too quickly. Therefore, do not mix these with urea. Also, if the diet already has more than 12% crude protein, there's no need to add urea.

Seventh, ensure the diet includes adequate levels of sulfur and phosphorus. These minerals enhance the utilization of urea in the rumen. Phosphorus can be added through bone meal, while sulfur can come from potassium sulfate or sodium sulfate. Balancing these nutrients improves the overall efficiency of urea use.

Eighth, avoid feeding urea to sick or very thin sheep. Also, don’t give urea to animals that are extremely hungry. Their digestive systems may not be ready to handle it, increasing the risk of toxicity. Always monitor the health and condition of your flock before introducing new supplements.

Ninth, the use of urea must be consistent. Continuous feeding allows the rumen microorganisms to adapt and function optimally. If you stop feeding urea for any reason, restart gradually, increasing the amount slowly to avoid shock to the system. Sudden changes can disrupt microbial balance and reduce effectiveness.

Tenth, be prepared to recognize and treat urea poisoning. Symptoms include restlessness, salivation, muscle tremors, and difficulty breathing. In case of poisoning, administer a rapid intravenous injection of 10% to 25% glucose solution—100 to 200 ml per dose. Additionally, giving 0.5 to 1 kg of vinegar orally can provide immediate relief and help neutralize the toxic effects of excess urea.

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