One, Trichoderma spp. Also known as Neurospora. The anamorphic stage is a species of the caterpillar family, Schizophyllaceae; the sexual stage is an ascomycete. Harmful mushrooms are R. crassa and R. crassa. Mycelium white, loose, branched and separated. Conidiophores are bifurcated branches. Conidiophore stroma, spherical to ovoid, orange or pink. Ascospora shells clustered or scattered, subglobose or ovate. Ascospora cylindrical, with 8 ascospores. Streptomyces is widely distributed, and air, soil, rotting plants, grains, etc. can spread. When the culture material is too wet and the tampon is damp, it occurs severely. It can pollute the parent species, original species, cultivated species, and ear sticks of mushrooms, fungus, and white fungus. The contaminated strains and culture materials grew grayish white bacterial filaments at an early stage and grew rapidly. After a few days, orange powdery spore masses were formed outside the bottle bags, which was significantly higher than the material surface. It often causes the batch bacteria to be scrapped. The prevention and control methods are: do a good job in environmental sanitation, thoroughly sterilize the culture materials, avoid the tampon being damp, and do not injure the bacteria bags when handling. Strictly abide by the aseptic procedures, and avoid high temperature and humidity in the culturing room. Regular inspections revealed that the spore masses were covered with wet paper and shipped out and burned. Second, Trichoderma. Also known as green mold. The head of the spores, plexiaceae. P. cinerea is Trichoderma viride and Trichoderma koningii. Mycelium is colorless and separated. Conidiophore stems emerge from the lateral branches of the mycelium, erect, septate, and often branching on small branches. The top small stalks are bottle-shaped, with conidial spores. Conidia spheroid or elliptic, pale green. Trichoderma on the damage of mushrooms are: pollution of culture materials, and mushrooms compete for nutrition; secrete toxins, poisonous mushroom mycelium; winding or cutting mushroom mycelium. It is widely distributed and is a worldwide pest. For a long period of time, the mushroom's growth process is infringed. A large degree of damage can make the whole batch of mushrooms not to be harvested. Trichoderma spp. is found in dead wood, plant residues, organic fertilizers, air and soil. Excessive carbon, high acidity, and high temperature and humidity conditions in the culture promote the occurrence of this. The residual roots that are left when picking mushrooms and are easily infested. Control methods: Keep the culture room low temperature, low carbon dioxide and ventilation. Anti-Trichoderma varieties were selected. Mushroom air humidity should not exceed 90%. After removing mushrooms, remove debris and roots in time. At the beginning of the infection, spray the 0.1% carbendazim solution or benomyl 800 times. With 0.1% carbendazim or thiophanate-methyl spices can prevent its occurrence. Third, Penicillium. Also belongs to the order of caterpillars, genus Stemona. Pesticides are Penicillium citrinum, Penicillium chrysogenum, and others. The mycelium is colorless or colored, with a transverse septum. Conidiophore septate septate, epiphyte-like branches, the top of the small stems, small stems connate conidia, conidia spherical or oval, pale green. Penicillium can grow on many organic materials. Conidia are mainly transmitted by air and can be produced all year round, especially in summer. On contaminated cultures, round colonies form, dark green to blue-green, and hairy, with slower expansion. When the colonies are dense, they are connected into pieces. The old colonies are often intertwined to form membranes that block the surface air and secrete toxins, which kills the mycelium. It can also induce mushroom diseases. Control methods: See control of Trichoderma and Trichoderma. Fourth, Aspergillus. Also belongs to the order of caterpillars, silk stems. Pests are Aspergillus niger, Aspergillus flavus, and Aspergillus niger. Mycelium is colorless and separated. Conidiophores without septa, without branching, apically dilated into spherical or elliptic, densely densely pedicellate, conidiophores spawned, globose or ovate, black (Aspergillus niger), yellowish green (Aspergillus flavus) or Light green (Aspergillus niger). Aspergillus is distributed on soil, air and various organic materials. High temperature, high humidity, poor ventilation, easy to occur when there are too many carbohydrates in the culture material. The contaminated culture began to appear white fluffy mycelium, which quickly turned into a colored layer of powdery mildew. It not only competes with the mushroom for nutrients and moisture, but also secretes toxins, which seriously affects the yield and quality of the mushroom. Control methods: control of Trichoderma spp. and Trichoderma spp.