Dental X-Ray Equipment,Dental Product,Dental Equipment Sofine Electric Co., Ltd. , http://www.sofine-dentistry.com
Description:
Clobetasol propionate is classed as a very potent topical corticosteroid. Topical corticosteroids are also referred to as topical steroids. Topical steroids are used in addition to moisturisers (emollients) for treating inflammatory skin conditions such as eczema and dermatitis. A topical steroid is used when patches of eczema or dermatitis flare up. Clobetasol propionate relieves the symptoms of a flare-up by reducing inflammation, itching and redness. It is not a cure for the condition, but it will help to relieve the symptoms.
Basic information:
Chemical name: Clobetasol propionate
MF: C25H32ClFO5
MW: 466.97
CAS: 25122-46-7
Appearance: white powder
Purity: 99%
Usage: anti-inflammatory agent
COA:
Â
Product name
Clobetasol propionate
CAS No.
25122-46-7
Outer Packing
1KG/bag
Production date
Sep.,08, 2016
Shelf life
Sep.,07, 2019
Standard adopted
USP38
Items of analysis
Specification
Results
Description
White or almost white crystalline powder
Almost white crystalline  powder
Solubility
Practically insoluble in water,slightly soluble in benzene and diethyl ether ,sparingly soluble ethanol Â
Complies
Identification (IR)
Complies with the Standard
Complies
Specific Rotation
+98°~+104° Â
+100.4°
Melting point
about 196ºC
195.0ºC~197.0ºC
Loss on drying Â
max.2.0%
0.20%
Residue on ignition
max. 0.1%
0.04%
Heavy Metals
max.20ppm
Complies
Single impurity
N.m.t 1.0%
0.16%
Sum impurity
N.m.t 2.5%
0.46%
Organic volatile impurities
meet the ICH requirement
Complies
Assay(HPLC,basisondrying)
98.5%~102.0%
99.9%
THF
Not more than 720ppm
Complies
Methanol
Not more than 3000ppm
Complies
DMF
Not more than 880ppm
Complies
Pyridine
Not more than 200ppm
Complies
Dichloromethane
Not more than 600ppm
Complies
Ethanol
Not more than 5000ppm
Complies
Acetone
Not more than 5000ppm
Complies
Conclusion
Qualified
Uses:
Clobetasol propionate is used for the treatment of various skin disorders including eczema, herpes labialis,psoriasis, and lichen sclerosus. It is also used to treat several auto-immune diseases including alopecia areata, lichen planus (auto immune skin nodules), and mycosis fungoides (T-cell skin lymphoma). It is used as first-line treatment for both acute and chronic GVHD of the skin.
Clobetasol proprionate is used cosmetically by dark-skinned women for skin whitening, although this use is controversial. The U.S. Food and Drug Administration has not approved it for that purpose, and sales without a prescription are illegal in the U.S. Nonetheless, it is often sold in U.S. retail beauty supply stores and on the internet. It is also sold internationally, and does not require a prescription in some countries. Whitening creams with clobetasol proprionate, such as Hyprogel, can make skin thin and easily bruised, with visible capillaries, and acne. It can also lead to hypertension, elevated blood sugar, suppression of the body's natural steroids, and stretch marks, which may be permanent.
Clobetasol propionate is, along with mercury and hydroquinone, "amongst the most toxic and most used agents in lightening products." Many products sold illegally have higher concentrations of clobetasol propionate than is permitted for prescription drugs.
How it works:
Clobetasol belongs to a class of drugs called topical corticosteroids. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions.
Clobetasol works by decreasing your body's response to inflammation. It also reduces the activity of your immune system. This prevents inflammation and itching and treats your skin condition.
INDICATIONS AND USAGE:
Clobetasol propionate cream is a super-high potency corticosteroid formulation indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid responsive dermatoses. Treatment beyond 2 consecutive weeks is not recommended, and the total dosage should not exceed 50 g per week because of the potential for the drug to suppress the hypothalamic-pituitary-adrenal (HPA) axis. Use in pediatric patients under 12 years of age is not recommended. As with other highly active corticosteroids, therapy should be discontinued when control has been achieved. If no improvement is seen within 2 weeks, reassessment of the diagnosis may be necessary.
Our  Advantage:Â
  High quality with competitive price:Â
  1)Standard: Enterprise Standard
  2)All Purity:>=99%
  3)We are manufacturer and can provide high quality products with factory price.Â
  Fast and safe delivery
  1)Parcel can be sent out in 24 hours after payment. Tracking number available
  2)Secure and discreet shipment. Various transportation methods for your choice.Â
  3)Customs pass rate: >=99%
  4) We have our own agent/remailer/distributor who can help us ship our products very fast and safe,    and we have stock in there for transferring.Â
  We have clients throughout the world.Â
  1)Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire.Â
  2)Market feedback and goods feedback will be appreciated, meeting customers's requirement is our responsibility.Â
  3) High quality, competitive price, fast delivery, first-class service gain the trust and praise from the customers.
How to proceed your orders:
Â
Step 1: Please let me know the items you are favorable, quantities, and the destination country.
Step 2: You confirm all details, and offer us purchasing order.
Step 3: We send the detail price of our product and offer the suitable shipping method for reference.
Step 4: You confirm the order and pay money 100% in advance and send us the detailed contacting information, including contacting person/company, address, mobile number,ZIP code and your special requirements.
Step 5: We arrange the shipment according to your requirements, and tracking code will be offered after claiming the payment within 24h, then you can track your parcel at any moment.
Step 6: We offer good after-sales service after you receive parcel.
If you have any questions, please feel free to contact me:
Tel: +8618872220738
Anti-inflammatory Drug Clobetasol propionate CAS: 25122-46-7 White Powder
Description:
Clobetasol propionate is classed as a very potent topical corticosteroid. Topical corticosteroids are also referred to as topical steroids. Topical steroids are used in addition to moisturisers (emollients) for treating inflammatory skin conditions such as eczema and dermatitis. A topical steroid is used when patches of eczema or dermatitis flare up. Clobetasol propionate relieves the symptoms of a flare-up by reducing inflammation, itching and redness. It is not a cure for the condition, but it will help to relieve the symptoms.
Basic information:
Chemical name: Clobetasol propionate
MF: C25H32ClFO5
MW: 466.97
CAS: 25122-46-7
Appearance: white powder
Purity: 99%
Usage: anti-inflammatory agent
COA:
Â
Product name
Clobetasol propionate
CAS No.
25122-46-7
Outer Packing
1KG/bag
Production date
Sep.,08, 2016
Shelf life
Sep.,07, 2019
Standard adopted
USP38
Items of analysis
Specification
Results
Description
White or almost white crystalline powder
Almost white crystalline  powder
Solubility
Practically insoluble in water,slightly soluble in benzene and diethyl ether ,sparingly soluble ethanol Â
Complies
Identification (IR)
Complies with the Standard
Complies
Specific Rotation
+98°~+104° Â
+100.4°
Melting point
about 196ºC
195.0ºC~197.0ºC
Loss on drying Â
max.2.0%
0.20%
Residue on ignition
max. 0.1%
0.04%
Heavy Metals
max.20ppm
Complies
Single impurity
N.m.t 1.0%
0.16%
Sum impurity
N.m.t 2.5%
0.46%
Organic volatile impurities
meet the ICH requirement
Complies
Assay(HPLC,basisondrying)
98.5%~102.0%
99.9%
THF
Not more than 720ppm
Complies
Methanol
Not more than 3000ppm
Complies
DMF
Not more than 880ppm
Complies
Pyridine
Not more than 200ppm
Complies
Dichloromethane
Not more than 600ppm
Complies
Ethanol
Not more than 5000ppm
Complies
Acetone
Not more than 5000ppm
Complies
Conclusion
Qualified
Uses:
Clobetasol propionate is used for the treatment of various skin disorders including eczema, herpes labialis,psoriasis, and lichen sclerosus. It is also used to treat several auto-immune diseases including alopecia areata, lichen planus (auto immune skin nodules), and mycosis fungoides (T-cell skin lymphoma). It is used as first-line treatment for both acute and chronic GVHD of the skin.
Clobetasol proprionate is used cosmetically by dark-skinned women for skin whitening, although this use is controversial. The U.S. Food and Drug Administration has not approved it for that purpose, and sales without a prescription are illegal in the U.S. Nonetheless, it is often sold in U.S. retail beauty supply stores and on the internet. It is also sold internationally, and does not require a prescription in some countries. Whitening creams with clobetasol proprionate, such as Hyprogel, can make skin thin and easily bruised, with visible capillaries, and acne. It can also lead to hypertension, elevated blood sugar, suppression of the body's natural steroids, and stretch marks, which may be permanent.
Clobetasol propionate is, along with mercury and hydroquinone, "amongst the most toxic and most used agents in lightening products." Many products sold illegally have higher concentrations of clobetasol propionate than is permitted for prescription drugs.
How it works:
Clobetasol belongs to a class of drugs called topical corticosteroids. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions.
Clobetasol works by decreasing your body's response to inflammation. It also reduces the activity of your immune system. This prevents inflammation and itching and treats your skin condition.
INDICATIONS AND USAGE:
Clobetasol propionate cream is a super-high potency corticosteroid formulation indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid responsive dermatoses. Treatment beyond 2 consecutive weeks is not recommended, and the total dosage should not exceed 50 g per week because of the potential for the drug to suppress the hypothalamic-pituitary-adrenal (HPA) axis. Use in pediatric patients under 12 years of age is not recommended. As with other highly active corticosteroids, therapy should be discontinued when control has been achieved. If no improvement is seen within 2 weeks, reassessment of the diagnosis may be necessary.
Our  Advantage:Â
  High quality with competitive price:Â
  1)Standard: Enterprise Standard
  2)All Purity:>=99%
  3)We are manufacturer and can provide high quality products with factory price.Â
  Fast and safe delivery
  1)Parcel can be sent out in 24 hours after payment. Tracking number available
  2)Secure and discreet shipment. Various transportation methods for your choice.Â
  3)Customs pass rate: >=99%
  4) We have our own agent/remailer/distributor who can help us ship our products very fast and safe,    and we have stock in there for transferring.Â
  We have clients throughout the world.Â
  1)Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire.Â
  2)Market feedback and goods feedback will be appreciated, meeting customers's requirement is our responsibility.Â
  3) High quality, competitive price, fast delivery, first-class service gain the trust and praise from the customers.
How to proceed your orders:
Â
Step 1: Please let me know the items you are favorable, quantities, and the destination country.
Step 2: You confirm all details, and offer us purchasing order.
Step 3: We send the detail price of our product and offer the suitable shipping method for reference.
Step 4: You confirm the order and pay money 100% in advance and send us the detailed contacting information, including contacting person/company, address, mobile number,ZIP code and your special requirements.
Step 5: We arrange the shipment according to your requirements, and tracking code will be offered after claiming the payment within 24h, then you can track your parcel at any moment.
Step 6: We offer good after-sales service after you receive parcel.
If you have any questions, please feel free to contact me:
Tel: +8618872220738
Model NO.: CAS: 81409-90-7
Delivery Time: Within 3-5 Days After Payment
Certificates: ISO9001
Grade: Pharmaceutical Grade
Express Way: EMS, FedEx, TNT, DHL, Hkems
Export Market: Global
Trademark: JCJ
Transport Package: Customized
Specification: usp
Origin: China
HS Code: 456789
Model NO.: CAS: 81409-90-7
Delivery Time: Within 3-5 Days After Payment
Certificates: ISO9001
Grade: Pharmaceutical Grade
Express Way: EMS, FedEx, TNT, DHL, Hkems
Export Market: Global
Trademark: JCJ
Transport Package: Customized
Specification: usp
Origin: China
HS Code: 456789
Anti-inflammatory Drug Clobetasol propionate CAS: 25122-46-7 White Powder