• Model NO.: 137862-53-4
  • Customized: Non-Customized
  • Suitable for: Adult
  • Purity: >99%
  • CAS: 137862-53-4
  • MW: 435.52
  • Grade: Pharma Grade
  • Lead Time: 1-2 Days Upon Receipt of Payment
  • Trademark: Saichuang
  • Specification: 450mg/ml
  • HS Code: 2905399090
  • Powder: Yes
  • Certification: HSE, ISO 9001, USP, BP
  • State: Solid
  • Synonym: L-Valine;Ambroxol Hydrochloride
  • Mf: C24h29n5o3
  • Appearance: White Powder
  • Usage: Antihypertensive
  • MOQ: 10g
  • Transport Package: as Required
  • Origin: China
USP Antihypertensive Intermediate Powder Valsartan CAS 137862-53-4


Quick Detail
Product Name
Valsartan
 
Synonym
L-Valine, N-(1-oxopentyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-;Ambroxol Hydrochloride Imp.D;3-Methyl-2-[pentanoyl-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]-butanoic aci;VALSARTAN IMP C;Valsartan;
 
CAS
137862-53-4
 
MF
C24H29N5O3
 
MW
435.52
 
Melting Point
116-117°C
 
Appearance
White Crystalline Powder
 
Solubility
DMSO: ≥20mg/mL
 
Uses
A nonpeptide angiotensin II AT1-receptor antagonist. Antihypertensive.
 
MOQ
10g
 


Description

1. Valsartan ( trade name Diovan ) is an angiotensin II receptor antagonist (commonly called an ARB,or
angiotensin receptor blocker ), that is selective for the type I ( AT1 ) angiotensin receptor. Valsartan is mainly used for treatment of high blood pressure, congestive heart failure, and to increase the chances of living longer after a heart attack.

2. Valsartan is used alone or in combination with other medications to treat high blood pressure. It is also used to treat heart failure (condition in which the heart is unable to pump enough blood to the rest of the body ) and to improve survival after a heart attack. Valsartan is in a class of medications called angiotensin II receptor antagonists. It works by blocking the action of certain natural substances that tighten the blood vessels, allowing the blood to flow more smoothly and the heart to pump more efficiently.

3. High blood pressure is a common condition and when not treated, can cause damage to the brain, heart, blood vessels, kidneys and other parts of the body. Damage to these organs may cause heart disease, a heart attack, heart failure, stroke, kidney failure, loss of vision, and other problems. In addition to taking medication, making lifestyle changes will also help to control your blood pressure. These changes include eating a diet that is low in fat and salt, maintaining a healthy weight, exercising at least 30 minutes most days, not smoking, and using alcohol in moderation.

Application

1. Valsartan is an angiotensin II receptor antagonist. Valsartan keeps blood vessels from narrowing, which lowers blood pressure and improves blood flow. Valsartan is used to treat high blood pressure ( hypertension ) in adults and children who are at least 6 years old. Valsartan is also used in adults to treat heart failure, and to lower the risk of death after a heart attack. Valsartan is sometimes given together with other blood pressure medications.
Valsartan may also be used for purposes not listed in this medication guide.

2. Valsartan is used to treat high blood pressure and heart failure. It is also used to improve the chance of living longer after a heart attack. In people with heart failure, it may also lower the chance of having to go to the hospital for heart failure. Valsartan belongs to a class of drugs called angiotensin receptor blockers (ARBs). It works by relaxing blood vessels so that blood can flow more easily. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems.

3. Valsartan is used to treat high blood pressure, congestive heart failure, and to reduce death for people with left ventricular dysfunction after having had a heart attack.There is contradictory evidence with regard to treating people with heart failure with a combination of an angiotensin receptor blocker like valsartan and an angiotensin - converting enzyme inhibitor, with two major clinical trials ( CHARM - additive and ValHeFt ) showing a reduction in death, and two others (VALIANT and ONTARGET ) showing no benefits, and more adverse effects including heart attacks. In people with type II diabetes and high blood pressure or albumin in the urine, valsartan is used to slow the worsening and the development end - stage renal disease.

COA:
ITEMS SPECIFICATION RESULTS
Appearance Off-white or white powder Conforms
Identification HPLC,NMR;LC-MS Conforms
Related substances Individual impurity≤0.5% 0.09%
Total impurities≤1.0% 0.20%
Loss on drying ≤0.5% 0.3%
Residue on ignition ≤0.1% 0.04%
Heavy metals ≤10ppm Conforms
Assay ≥98.0 % 99.1%


Package And Shipping:

USP37 CAS Rn	137862-53-4 Valsartan


Advantage:

1. Rich Experiences.
Our company has been dealt in the pharmaceutical manufacturing area for many years. Delivery areas of our products extend all around the world. we have got very good feedback from our customers of worldwide, we had established a long friendly relations and enjoyed a high reputation both at home and abroad.
Payment method: T/T, Western Union, Money Gram.

2. Discreet package.
The package suits you best would be chosen to get through customs security smoothly or customized if you want.

3. Superior quality and Reasonable price.
High quality guaranteed, once any problem is found, the goods would be reshipped for you.

4. Security Shipping.
Shipping by express (FedEx,UPS,DHL,EMS) or by air. The most professional forwarder would be recommended for you.

5. We have stock.
We can delivery goods promptly at the same day after confirming the payment.

6. Discounts.
We will do some promotion at the specific time, we would inform you anytime if we have sorts of discount activities. We can give you some discounts if you order a large number of goods.

7. Warm after-sale service for you 24/7.
Any of your question would be solved for the first time asap. Adhering to the principle of customer first conviction. we will provide the best and the most sincere services for your satisfaction.

 

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