Release date: 2017-09-05

A scientist from the University of Science and Technology in Australia is conducting a study that may take us one step closer to 3D bioprinting of human tissue for transplantation and regeneration.

The project, led by doctoral student Lilith Caballero Aguilar, involves developing a method to control the rate and frequency of growth factor release, which is critical for the development and survival of implanted stem cells.

In other words, when a 3D bioprint stem cell structure is implanted, it can take up to six weeks to convert to a particular type of cell, such as cartilage. In order to transform stem cells, it is necessary to slowly release growth factors.

To achieve this, Caballero Aguilar is developing polymer materials that can be used as a release mechanism for growth factors. She is said to be using an emulsification process that quickly shakes water and oil to create tiny "microspheres" in solution that can be crosslinked to produce a material suitable for controlling growth factors.

Other participants in the study included members from BioFab3D @ ACMD. BioFab3D @ ACMD is the first bioengineering laboratory to operate in an Australian hospital, co-founded by the St. Vincent Hospital in Melbourne, where the University of Science and Technology, the Royal Melbourne Institute of Technology, the University of Melbourne, the University of Wollongong and the laboratory are located.

In this laboratory context, Caballero Aguilar works closely with the hospital's orthopaedic surgeons and muscle specialists to advance her research in a practical way.

Currently, BioFab3D @ ACMD Labs is conducting two major bioengineering projects: one focused on cartilage regeneration and the other focused on the repair and regeneration of damaged muscle fibers. Caballero Aguilar's 3D bioprinting research may have a tangible impact on both projects.

(Compiled from 3ders.org)

Source: Tiangongshe

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