New research finds key proteins that affect asthma October 23, 2018 Source: Xinhuanet A new study published by the Francis Crick Institute in the United Kingdom found that a protein plays a key role in regulating allergic airway inflammation, and the mechanisms help to find better asthma treatments in the future. Asthma is a common chronic airway inflammation, often leading to recurrent wheezing, shortness of breath, chest tightness, cough and other symptoms, seriously affecting the quality of life of patients. The Crick Institute collaborated with Imperial College of Technology and Genentech to use specially cultured mice in the laboratory to observe how a protein called "ABIN-2" affects airway inflammation caused by dust mites. The researchers found that dendritic cells in the lungs of mice capture allergens in the airways and activate the immune system. If the "ABIN-2" protein is prevented from acting as a key signal, dendritic cells secrete more tiny signal proteins called "CCL24." This protein exacerbates inflammation in the airways and produces mucus, which eventually leads to severe allergic airway inflammation in mice. One of the report's authors, Dr. Wilson of Genentech, said the study may have been able to prevent severe airway inflammation and asthma by regulating the signaling role of the "ABIN-2" protein in dendritic cells. Related research has been published in the new issue of the American Journal of Experimental Medicine. Jewelry Safes,Jewelry Safe,Best Jewelry Safe,Jewelry Safe Box Hebei Yingbo Safe Boxes Co.,Ltd , https://www.yingbosafebox.com