GHRP-2

   

 

GHRP-2 Peptide

 

Sequence: H-D-Ala-D-2-Nal-Ala-Trp-D-Phe-Lys-NH2
Molecular formula: C45H55N9O6
Molar Mass: 817.9
CAS number: 158861-67-7
PubChem: CID 6918245 
Synonyms: Grow Hormone Releasing Peptide-2; GHRP2; GHRP 2

Grow Hormone Releasing Peptide 2

 

GHRP-2 and GRF Analogue Interactions (CJC-1295 / Sermorelin)

It is important to know that GHRP-2 does not relate to any Grow Hormone Releasing Hormones (GHRH) peptides such asSermorelin and CJC-1295 because it acts on different receptors. However, greater results occurred when administered in conjunction with a Grow Hormone Releasing Hormone (GHRH) such as Modified GRF 1-29 or CJC-1295 DAC. Naturally, these GHRP-2 peptide receptors interact with a hormone called ghrelin. Grow hormone releasing peptide 2 is a commercially synthesized, non-natural super-analog of GHRP-6 which is capable of potent stimulatory effect on growth hormon(GH) secretion with slight stimulator effect in PRL, ACTH and levels of cortisol (Arvat et al. 1997). It is also a synthetic agonist of ghrelin that is binding with the growth hormon (GH) secretagogue receptor. GHRP-2 has been shown to affect and induce growth hormon secretion. The response of natural physiologic system includes increase in levels of calcium ion influx alongside with increased release of growth hormon in response to this peptide (Wu et al. 1994)

The Utility of GHRP-2 as a Grow Hormone Secretagogue

GHRP-2 has been studied extensively for its utility as a grow hormone secretagogue (GHS). Scientists have discovered that the Growth Hormon Releasing Peptide-2 increases the natural production of grow hormone (GH). In the early 90's, one of the most famous studies was performed and later published in 1997 in the Journal of Endocrinology and Metabolism. This study further exemplifies the theory that growth hormon releasing peptides (including Ipamorelin and GHRP-6) could help hormone deficient adults and children. Ever since these major scientific studies, GHRP-2 has been widely produced. With other scientific labs confirming the results from their studies, GHRP-2 can in fact work for those who lack the ability to make adequate human grow hormone. Results however will differ with the use of GHRP-2 because species respond differently based on the pituitary somatotrophs and the differences in the subtypes of GHRP receptors. In the physiologic system, the actions are blocked by GRF receptors antagonist which acts through a different receptor to that employed by earlier GHRPs.

GHRP-2

   

 

GHRP-2 Peptide

 

Sequence: H-D-Ala-D-2-Nal-Ala-Trp-D-Phe-Lys-NH2
Molecular formula: C45H55N9O6
Molar Mass: 817.9
CAS number: 158861-67-7
PubChem: CID 6918245 
Synonyms: Grow Hormone Releasing Peptide-2; GHRP2; GHRP 2

Grow Hormone Releasing Peptide 2

 

GHRP-2 and GRF Analogue Interactions (CJC-1295 / Sermorelin)

It is important to know that GHRP-2 does not relate to any Grow Hormone Releasing Hormones (GHRH) peptides such asSermorelin and CJC-1295 because it acts on different receptors. However, greater results occurred when administered in conjunction with a Grow Hormone Releasing Hormone (GHRH) such as Modified GRF 1-29 or CJC-1295 DAC. Naturally, these GHRP-2 peptide receptors interact with a hormone called ghrelin. Grow hormone releasing peptide 2 is a commercially synthesized, non-natural super-analog of GHRP-6 which is capable of potent stimulatory effect on growth hormon(GH) secretion with slight stimulator effect in PRL, ACTH and levels of cortisol (Arvat et al. 1997). It is also a synthetic agonist of ghrelin that is binding with the growth hormon (GH) secretagogue receptor. GHRP-2 has been shown to affect and induce growth hormon secretion. The response of natural physiologic system includes increase in levels of calcium ion influx alongside with increased release of growth hormon in response to this peptide (Wu et al. 1994)

The Utility of GHRP-2 as a Grow Hormone Secretagogue

GHRP-2 has been studied extensively for its utility as a grow hormone secretagogue (GHS). Scientists have discovered that the Growth Hormon Releasing Peptide-2 increases the natural production of grow hormone (GH). In the early 90's, one of the most famous studies was performed and later published in 1997 in the Journal of Endocrinology and Metabolism. This study further exemplifies the theory that growth hormon releasing peptides (including Ipamorelin and GHRP-6) could help hormone deficient adults and children. Ever since these major scientific studies, GHRP-2 has been widely produced. With other scientific labs confirming the results from their studies, GHRP-2 can in fact work for those who lack the ability to make adequate human grow hormone. Results however will differ with the use of GHRP-2 because species respond differently based on the pituitary somatotrophs and the differences in the subtypes of GHRP receptors. In the physiologic system, the actions are blocked by GRF receptors antagonist which acts through a different receptor to that employed by earlier GHRPs.